The discovery of the DNA double helix

Many people believe that the American biologist James Watson and the English physicist Francis Crick discovered DNA in the 1950s. Actually, this is not the case. Rather, the DNA was first identified in the late 1860s by the Swiss chemist Friedrich Miescher. this news was the most novel of the last century but in the actulidad if you want to have new and renewed information you can visit this site feeds.ramisp.

Then, in the latest versions of Miescher’s discovery, other scientists, in particular, Phoebus Levene and Erwin Chargaff, conducted a series of investigations that revealed more details about the DNA molecule, including the primary components and the ways in which they united one with the other. Without the scientific basis provided by these pioneers, Watson and Crick could never have reached their revolutionary conclusion of 1953: that the DNA molecule exists in the form of a three-dimensional double helix image.

The first piece of the puzzle: Miescher discovers DNA

Few people realize 1869 was a key year in genetic research, because it was the year in which Friedrich Miescher, physiological chemist, first identified what he called “nucleus” within the nuclei of white blood cells . (The term “nuclein” was later changed to “nucleic acid” and finally to “deoxyribonucleic acid,” or “DNA.”) Miescher’s plan was isolated and characterized not by nuclein (which no one at that time realized) ), the components of leukocytes (white blood cells).

Miescher thus arranged for a local surgical surgery to send pus remnants covered with patient bandages, and once he received the bandages, he managed to wash them, filter the leukocytes, and extract and identify the different proteins within the white blood cells. But when he found a substance from the nucleus of cells that have different chemical properties, it became a protein of the protein that was discovered in a new protein. substance (Dahm, 2008). Being the importance of his findings, Miescher wrote: “It is likely that a whole family of molecules with those slight variations that contain phosphorus, are like a group of nuclei, equivalent to proteins” (Wolf, 2003).

More than 50 years before the importance of the discovery of Miescher of nucleic acids was very appreciated by the scientific community. For example, in a 1971 essay on the history of nucleic acid research, Erwin Chargaff points out in 1961 in a retelling of the history of nineteenth-century science, Charles Darwin was mentioned 31 times, Thomas Huxley 14 times, but Miescher not even once. This omission is all the more remarkable, since, like Chargaff also, the discovery of nucleic acids was the only one among the major cellular components (ie, proteins, lipids, polysaccharides and nucleic acids) that can be “precisely dated … [ like] a man, a place, a date. “